Key takeaways
- BPC-157 is a 15-amino-acid peptide derived from a gastric protein sequence.
- TB-500 is a synthetic peptide based on the active region of Thymosin Beta-4.
- Both are studied in preclinical tissue repair models, through different proposed mechanisms.
- Labs often study them together, which is why a BPC-157 + TB-500 blend exists.
Two peptides, two origins
BPC-157 is a synthetic pentadecapeptide derived from a protein in gastric juice. TB-500 is a synthetic peptide modelled on the active region of Thymosin Beta-4, a protein naturally found in many tissues.
Because they come from different proteins, they have different sequences, molecular weights and proposed mechanisms in research.
How their research focus differs
BPC-157 research frequently looks at gastrointestinal, tendon and ligament models, and at angiogenesis and growth factor signalling.
TB-500 research often focuses on actin regulation, cell migration and wound healing models, reflecting the known role of Thymosin Beta-4 in binding actin. As with BPC-157, this work is mainly preclinical.
Why researchers study them together
Since the two peptides are investigated for related outcomes through different pathways, some labs study them side by side or in combination. Our BPC-157 + TB-500 blend supplies both in a single lyophilized vial for that purpose.
Quality checks for both peptides
Whichever peptide you study, verify the lot COA. Alpha Peptides tests BPC-157, TB-500 and the blend through Prism Labs, with HPLC purity and mass spectrometry identity results for each lot.
Every lot comes with a COA
Independent HPLC chromatograms and mass spectrometry from Prism Labs, Canada's independent peptide testing lab. Match your vial's lot number to its certificate.
Frequently asked questions
What is the main difference between BPC-157 and TB-500?
BPC-157 derives from a gastric protein sequence, while TB-500 is based on Thymosin Beta-4. They differ in structure and proposed research mechanisms.
Can BPC-157 and TB-500 be studied together?
Yes. Some preclinical research looks at both, and a combined BPC-157 + TB-500 research blend is available.
Where can I buy BPC-157 and TB-500 in Canada?
Alpha Peptides ships both peptides and the blend Canada-wide, each with a Prism Labs Certificate of Analysis.
Are BPC-157 and TB-500 approved for human use?
No. Both are sold for in-vitro laboratory research only and are not approved by Health Canada for human use.
Keep reading
Peptide Guides
What Is BPC-157? A Complete Research Guide for Canada
BPC-157 explained: origin, amino acid sequence, what preclinical studies investigate, purity testing and where to buy BPC-157 in Canada.
Handling & Storage
How to Store Lyophilized Research Peptides
Best practices for storing lyophilized and reconstituted research peptides: temperature, light, moisture and handling tips for Canadian labs.
For in-vitro laboratory research only. Not for human or animal use. Not approved by Health Canada for human consumption.